产品货号：
Z26073
中文名称：
Rubicon/RUBCN抗体
英文名称：
Anti-Rubicon/RUBCN Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Rubicon/RUBCN Antibody |
| 指标别名 | Baron,KIAA0226,RUBCN,Rubicon |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | RUBCN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Rubicon antibody was raised against a 16 amino acid peptide near the amino terminus of human Rubicon.The immunogen is located within amino acids 240 - 290 of Rubicon. |
| 计算分子量 | 109kDa |
| 成分 | Rubicon antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Rubicon antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Two Beclin-1-interacting proteins,the run domain Beclin-1 interacting and cysteine-rich containing protein (Rubicon) and ATG14L,reciprocally regulate autophagy at different stages.Knockdown of Rubicon caused enhancement of autophagy while that of ATG14L caused a defect in autophagosome formation (1).Rubicon functions as part of a Beclin-1-PIK3C3-containing autophagy complex and is also an essential,positive regulator of the NAPDH oxidase complex (2).Upon microbial infection or TLR2 activation,Rubicon interacts with the CYBA subunit of the NAPDH oxidase complex,leading to a burst of reactive oxygen species and inflammatory cytokines (2). |
| Uniprot ID | Q92622 |
| 基因名全称 | KIAA0226 |
| 蛋白名全称 | KIAA0226 |
| 推荐稀释比 | Rubicon body can be used for detection of Rubicon by Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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